6-Maleimidocapronic acid( —— )

Catalog No. M24546 CAS No. 55750-53-3

6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

6-Maleimidocapronic acid
Note

Research use only, not for human use.
Brief Description

6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

——
Pathway

PROTACs
Target

PROTAC
Recptor

Alkyl-Chain
Research Area

——
Indication

——

Chemical Information

CAS Number

55750-53-3
Formula Weight

211.21
Molecular Formula

C10H13NO4
Purity

>98% (HPLC)
Solubility

DMSO: 190 mg/mL (899.58 mM; Need ultrasonic)
SMILES

O=C(N1CCCCCC(O)=O)C=CC1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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